Additionally, airway resistance, airway closure, airway narrowing, and the presence of secretions can also impact the amount of physiological dead space. Factors that affect physiological dead space include the size of the airways, the size of the alveoli, and the amount of air in the alveoli. Physiological dead space, on the other hand, is the volume of air in the conducting airways plus the alveoli that do not participate in gas exchange. Anatomical dead space is defined as the volume of air in the conducting airways of the respiratory system that does not participate in gas exchange. The differences between anatomical and physiological dead space can have a significant impact on an individual’s health.
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